Monday, August 29, 2011

Adiponectin In Insulin Resistance



What is insulin resistance? Insulin resistance is a condition where the concentration of insulin in the body are very high but the body does not respond properly to insulin, so as if the deficiency of insulin. As a result, blood sugar contained in our bodies can not be balanced or excess blood sugar and eventually someone can get diabetes.Type diabetes resulting from insulin resistance were classified as type 2 diabetes or type 2 diabetes mellitus.


What is adiponectin? Today has found a protein involved in insulin resistance is adiponectin. Adiponectin is one of the proteins that have important effects in maintaining the balance of sugar and fat. Adiponectin function in increasing the sensitivity / sensitivity of the organs of the body to insulin so that play a role in regulating the balance of sugar in the body. In normal conditions, adiponectin will maintain the balance of blood sugar through the reduction of sugar produced by the liver and maximize the use of sugar by the organs of the body that need sugar as an energy source.


The concentration of adiponectin in the body will decrease in the state of obesity (overweight) and insulin resistance. Low concentrations of adiponectin are found in individuals with insulin resistance, regardless rather than whether they are obese (overweight) or not. These findings suggest that low adiponectin concentrations directly contribute to the setting changes the balance of sugar and decrease insulin sensitivity in the liver.


Adiponectin examination is also useful to look at the risk of future diabetes because adiponectin plays a role in maintaining the balance blood sugar metabolism in the body. Individuals who have risk factors are those that have diabetes family descendants. They can conduct examination of adiponectin to view the possibility of occurrence of diabetes in the future.


Increased concentrations of adiponectin associated with the regulation of sugar concentration is better, better lipid profile and decreased inflammation (inflammatory) infection in individuals with insulin resistance and diabetes sufferers. Determination of the concentration of adiponectin is critical to determine the risk of Coronary Heart Disease (CHD) in people with diabetes.



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